|
|
|
| SP - TRISAMINE RESIN, MP - FINE |
| PRODUCT: |
| SP–Trisamine Resin, MP - Fine is solid-supported Trisamine on a mixed bed of macroporous polystyrene and silicates. |
| |
| APPLICATIONS: |
- SP-Trisamine Resin, MP - Fine is a polyamine-functional resin that is highly effective in scavenging excess electrophilic reagents, such as acid chlorides, sulfonyl chlorides, and isocyanates during the quenching and purification of reaction mixtures.
- It is highly effective in scavenging of metals such as palladium, platinum, lead, nickel, cobalt, chromium and copper.
- SP-Trisamine Resin MP - Fine has a highly cross-linked macroporous resin backbone, hence it is not dependent on swelling to be effective, making it compatible with a broad range of solvents including highly polar solvents including DMF, acetonitrile and water.
|
| PROPERTIES: |
Resin Type: Mixed bed of Macroporous polystyrene and silicates
Loading: 2.1 - 2.0 mmol/g (based on benzoyl chloride uptake)
Bead Size: 100-200 mesh (>90% within)
|
| Typical Scavenging: |
3-5 equiv relative to acid chloride, 1-4 h, 20°C. If an additional resin-bound base is present: 1.5-3 equiv |
| Compatible Solvents: |
DCM, DMF, THF, MeOH, any non-acidic organic solvents, acetonitrile and water |
| |
|
|
| REFERENCES: |
- Bhattacharyya, S.; Fan, L.; Vo, L.; Labadie, J. Combi Chem & High Throughput Screen, 2000, 3, 117.
- Gooding, O.; Labadie, J.; Porco,J. J. Comb. Chem, 1999, 1, 420-422.
- Booth, R.T.; Hodges, J.C. J. Am. Chem. Soc, 1997, 119, 4882.
|
|
|
|
|
